You are here:  Home > Services > Cheminformatics > Pharmacophore Modeling

Pharmacophore Modeling
Within the last few years, pharmacophore modeling has become the most important ligand-based drug design technique. We at Evolvus, employ various commercial as well as in-house softwares for developing pharmacophore models. Generated models are validated using in combo approaches. We also undertake pseudo-receptor modeling, particularly for GPCRs, which involves generation of a target protein's active site based on structural requirements complementary to the generated pharmacophore.